Cross-bridge cycle | Skeletal muscle contraction

00:00 : Introduction to video
00:18 : Sarcomeres are made up of myosin, actin.
1:44 : ATP is broken down to power muscle contraction
1:59 : Calcium allows for myosin to bind to actin
2:27 : The power stroke generates force
2:42 : ATP binds myosin, causing muscle relaxation
3:06 : Summary of all the steps involved in the cross bridge cycle.
4:05 : Definition of the sliding filament theory of muscle contraction

Full explanation of skeletal muscle contraction:    • Excitation Contraction Coupling and the Ne...  

In this video, we review the cross-bridge cycle and the steps that lead to skeletal muscle contraction. We'll review the power stroke, how ATP and calcium are involved, and the role of key proteins like tropomyosin and troponin. We also introduce the rigor state, in which myosin stays bound to actin.

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