Dr. Christopher Rowley - Optimizing acquisition parameters for inhomogeneous magnetization transfer

Quantitative Magnetic Resonance Imaging Conference: Applications in Neurodegeneration (October 26-28th 2022)

Myelin Water Imaging - Trainee talk 3

Dr. Christopher Rowley - Optimization of acquisition parameters for cortical inhomogeneous magnetization transfer (ihMT) imaging

Biography: Post doctoral Researcher, McGill University, Montreal QC, Canada.

Abstract: Imaging biomarkers with increased myelin specificity are needed to better understand the complex progression of many neurological disorders. Inhomogeneous magnetization transfer (ihMT) imaging is an emergent technique with a high degree of specificity for myelin content but suffers from a low signal-noise ratio (SNR). In this study, numerical simulations using Bloch-McConnell equations were used to uncover acquisition parameters that provide optimal ihMT SNR for high resolution cortical ihMT imaging. The simulation results were used to select a 1 mm isotropic ihMT protocol that can be acquired in under 20 minutes. These findings will permit the use of myelin-specific, high-resolution imaging to study the complexities of cortical microstructure in vivo

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Organizing Committee

Dr. Mallar Chakravarty (@mallarchkrvrty1)
Dr. Christine Lucas Tardif (@tardiftweets)
Dr. Christopher Rowley (@rowleycd)
Aurélie Bussy (@AurelieBussy)
Olivier Parent (@oparent41)