How MPS2 Determines if a Prostate Biopsy is necessary I Jeff Tosoian, MD –148

#ProstateCancer #ProstateHealth #MPS2 #MyProstateScore #MensHealth
Are we entering a new era of prostate cancer testing? In this episode, Dr. Geo speaks with Dr. Jeffrey Tosoian—urologist, researcher, and lead author behind MyProstateScore 2.0 (MPS2)—a cutting-edge urine test that may outperform PSA and even MRI in identifying clinically significant prostate cancer.

Learn:

🔬 How MPS2 works and what makes it different from PSA, 4Kscore, and ExoDx

✅ Why MPS2 offers a 95%+ negative predictive value (NPV) — helping men avoid unnecessary prostate biopsies 💉🚫

🧠 When to use MRI vs. biomarker testing 🧪

🌍 How this test may improve outcomes for populations with limited access to 3T MRI, including Black men and underserved communities 🏥

🚨 How MPS2 could become a game changer for men on active surveillance 🔎📈

🧪 This test includes 18 prostate cancer-specific gene markers and is now available without a rectal exam. It can even be done from home. Dr. Tosoian explains everything—from clinical validation to future directions.

👉 Ask your doctor about MyProstateScore 2.0 (MPS2) or visit Lynx Dx: https://bit.ly/4mOHQ2U to learn more.

📚 Chapters
00:00 Better Than PSA – How MyProstateScore 2.0 with Dr. Jeffrey Tosoian
02:32 The Importance of Minimizing Unnecessary Biopsies
03:23 Advancements in Prostate Cancer Screening: MyProstateScore 2.0
03:40 The Role of PSA and Biomarkers in Prostate Cancer Detection
05:17 MRI vs. Biomarkers: Choosing the Right Diagnostic Tool
09:37 Understanding Negative Predictive Value in Prostate Cancer Tests
11:18 The Development and Validation of MyProstateScore 2.0
15:47 Practical Considerations and Real-World Application of MPS 2.0
24:24 Detailed Explanation of MyProstateScore 2.0
29:39 Advancements in Prostate Cancer Biomarkers
30:36 Understanding High-Grade Prostate Cancer
33:06 Challenges with MRI in Prostate Cancer Detection
34:37 Addressing Neuroendocrine Prostate Cancer
35:45 The Role of Lifestyle in Prostate Cancer Management
37:44 How MyProstateScore 2.0 Works
43:29 Racial Diversity and Prostate Cancer Testing
49:39 Active Surveillance and Biomarkers

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📌 Thank You to Our June Sponsors

LynxDx – https://bit.ly/4mOHQ2U
Discover MyProstateScore 2.0 (MPS2), the next-generation urine test that helps you understand your prostate cancer risk. MPS2 analyzes a powerful panel of 18 biomarkers to deliver a personalized risk score, helping you and your doctor decide if further testing or a biopsy is right for you. MPS2 brings clarity and convenience to your prostate cancer screening journey with easy at-home or in-office collection. Visit lynxdx.com to learn more.

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📌 Support Your Urological Health

XY Wellness – Prostate cancer lifestyle and nutrition: https://bit.ly/3uJPC7Z

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#Biomarkers #PSAtest #ActiveSurveillance #Urology #ProstateBiopsy #DrGeoPodcast #LynxDx

DISCLAIMER: This audio is educational and not medical advice. The views expressed are my own and not those of my employer(s) or affiliated organizations. Use of this content is at your own risk. Geovanni Espinosa, N.D., assumes no liability for any direct or indirect consequences, including economic loss, injury, illness, or death.