Windows 10 Enterprise LTSC and Windows 10 IoT Enterprise LTSC are both long-term

Windows 10 Enterprise LTSC and Windows 10 IoT Enterprise LTSC are both long-term servicing channel (LTSC) versions of Windows 10, designed for stability and predictable performance in specific environments. The main difference lies in their intended use and licensing: LTSC is for general enterprise use, while IoT LTSC is specifically for dedicated-purpose devices like point-of-sale systems or industrial machines.
Windows 10 Enterprise LTSC:

Intended use:
For general enterprise environments where stability and compatibility are prioritized over frequent feature updates.

Licensing:
Licensed through Microsoft Volume Licensing, typically tied to an end-user.
Support:
Receives security updates for 5 years after the release of the specific LTSC version.
Features:
Includes the core features of Windows 10 Enterprise, but with no feature updates.

Windows 10 IoT Enterprise LTSC:

Intended use:
For dedicated-purpose devices (IoT devices) where stability and long-term support are crucial, and frequent updates can disrupt operations.

Licensing:
Licensed directly to IoT device manufacturers (OEMs) for dedicated use devices.
Support:
Receives security updates for 10 years after the release of the specific LTSC version.
Features:
Includes the core features of Windows 10 Enterprise, tailored for IoT devices, with no feature updates.

Key Differences:

Target Audience:
LTSC is for general enterprise use, while IoT LTSC is for dedicated IoT devices.

Licensing:
LTSC is licensed through volume licensing, while IoT LTSC is licensed to OEMs.
Support Lifespan:
Both have a long-term support lifecycle (LTSC), but IoT LTSC typically has a longer support period.
Features:
Both are LTSC versions with no feature updates, but IoT LTSC may have some features specifically designed for IoT devices.

In essence: If you need a stable, predictable operating system for a dedicated-purpose device with long-term support, Windows 10 IoT Enterprise LTSC is a good choice. If you need a stable OS for general enterprise use, Windows 10 Enterprise LTSC is a suitable option.