CVS PHYSIOLOGY-LEFT VENTRICLE,systemic vascular resistance Dr Tyler Peck * HARVARD

00:00 Introduction and welcome.

02:10 Main topic begins: focus on left ventricular physiology and systemic vascular resistance.
08:00 Case introduction with a patient scenario of cardiogenic shock
13:30 Detailed explanation of pressure-volume loops and heart failure mechanics.

24:00 Hemodynamic assessment in the ICU, including using pulmonary artery catheters.
32:00 Discussion about the evolution and selective use of pulmonary artery catheters.
41:00 Classification of shock stages and patient phenotyping.

50:00 Management strategies: inotropes, vasopressors, and mechanical support.

1:03:00 discussion and closing remarks.
1:09:00 Final thoughts on systemic vascular resistance and individualizing therapy.

CU Cardiovascular Physiology Overview
DR Tyler presented on cardiovascular physiology in the ICU, focusing on left ventricular failure and systemic vascular resistance. He discussed the pathophysiology of heart failure, including the concept of ventricular-arterial coupling and the role of systemic vascular resistance in left ventricular afterload. Tyler also covered hemodynamic assessment methods in the ICU, including pulmonary artery catheterization, point-of-care ultrasound, and arterial line waveform analysis. He emphasized the importance of early recognition and management of cardiogenic shock, highlighting a case study of a patient with anterior ST elevation myocardial infarction and severe multivessel coronary disease.

Pulmonary Catheters in Cardiogenic Shock
Tyler discussed the use of pulmonary artery catheters in the ICU, focusing on their role in diagnosing and managing cardiogenic shock. He explained the hemodynamic profiles associated with different types of shock and outlined treatment strategies, including the use of vasodilators, inotropes, and vasopressors. Tyler emphasized the importance of individualizing therapy based on each patient's unique hemodynamic profile and discussed the role of mechanical circulatory support in severe cases. He also addressed questions from the audience about the use of vasopressors versus inotropes and the relationship between right atrial pressure and left ventricular failure.