Schizophrenia and Dopamine (Level 3 - Advanced)

This video provides an introduction to schizophrenia, its relation to dopamine, the different families of dopamine receptors, psychosis, and anti-psychotic drugs. You have probably heard of both schizophrenia and dopamine, but did you know that they are intimately related?

If you'd like a shorter and less technical version of this topic, check out the other difficulty levels of this video:
Level 1 (Beginner - 1 minute):    • #Dopamine and #Schizophrenia (Level 1 - Be...  
Level 2 (Intermediate - 20 minutes):    • Schizophrenia and Dopamine (Level 2 - Inte...  

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Chapters:
00:00 What do you think of when you hear the word "dopamine"?
00:45 Schizophrenia drugs take advantage of dopamine biology
01:40 I'm Andrew, this is Sense of Mind, and this series on neuroscience and dopamine.
03:48 Do you need an introduction to action potentials, neurotransmitters, etc? (CARD)
04:23 Check out levels 2 and 1 of this video (CARD)
04:40 What is dopamine?
05:30 Dopamine is involved in a lot of functions
06:42 Where dopamine is produced and localized in the brain.
07:25 Two families of dopamine receptors (D1 and D2)
08:22 The mechanisms of D1 and D2 receptors
10:03 Functions of the D1 and D2 receptors
12:00 The 3D structure of dopamine receptors
13:00 Expression patterns of D1 and D2 receptors in the brain and neurons
16:17 What is schizophrenia? What are the symptoms?
17:50 Speaking Oddly: A symptom of schizophrenia
20:20 What causes schizophrenia? Nature + Nurture factors
24:32 The schizophrenic brain, visualized
29:15 Blocking D2 dopamine receptors helps with symptoms of schizophrenia. How?
32:34 Thank you so much for watching! Please like, comment, follow, and subscribe!

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Sources and Recommended Readings:

Hyman, S. E. (2021). Disorders of Thought and Volition in Schizophrenia. In J. Gordon (Ed.), Principles of Neural Science (6th ed., pp. 1488–1500). essay, McGraw-hill.

Banich, M. T., & Compton, R. J. (2018). Cognitive neuroscience. Chapter 1: Introduction to the Nervous system. Cambridge University Press.

Beaulieu, J. M., Espinoza, S., & Gainetdinov, R. R. (2014). Dopamine receptors–IUPHAR R eview 13. British journal of pharmacology, 172(1), 1-23.

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