Microcystic adnexal carcinoma explained by a dermatopathologist. Dermpath made easy.
Автор: Dr. Michael Lee
Загружено: 2019-03-11
Просмотров: 931
Microcystic adnexal carcinoma - This is a biphasic malignant sweat duct tumor with ductal and follicular differentiation.
This is a bump or plaque typically on the upper lip, cheek or chin of older individuals. The tumor grows very slowly over the course of years.
Keys to the diagnosis:
1. Poorly circumscribed and deeply infiltrative
2. Lymphoid aggregates typically found
3. Perineural invasion common
4. Biphasic: horn cysts (follicular differentiation) + paisley tie ductal structures, common superficially.
5. The tumor is infiltrative, in thin cords and duct-like nested structures.
6. Dense sclerotic collagen rich stroma.
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