Rahul Gaurav - Abnormal iron concentration in PD in the posteroventral nigral region over time

Quantitative Magnetic Resonance Imaging Conference: Validation of Quantitative MRI techniques (November 29th-December 1st 2023)

Validation of susceptibility metrics - Short talk

Rahul Gaurav - Abnormal iron concentration in PD patients in the posteroventral nigral region and not in any other basal ganglia region over time

Biography: Paris Brain Institute (ICM), Sorbonne University, France

Abstract: Although Parkinson’s disease (PD) demonstrates substantia nigra (SN) iron overload, regional changes are poorly understood. Subjects were assessed 3 times 2 years apart. Mean quantitative susceptibility mapping template was developed. Iron was quantified in SN, its subdivisions, subthalamic nucleus, caudate nucleus, putamen, globus pallidus and thalamus. PD without REM sleep behavior disorder showed 17.8% and during the follow up, 26.2% posteroventral SN iron overload with respect to controls.

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Dr. Mallar Chakravarty (@mallarchkrvrty1)
Dr. Christine Lucas Tardif (@tardiftweets)
Dr. Christopher Rowley (@rowleycd)
Dr. Aurélie Bussy (@AurelieBussy)
Olivier Parent (@oparent41)
Sajjad Feizollah (@SajjadFeizollah)
Mark Nelson (@Mark_Cameron_)