DNA Replication Explained Step-by-Step | Class 12 Biology | Lec 7

Welcome to BioFlow!
In this detailed lecture, I explain the process of DNA replication — how genetic information is copied during cell division.
This topic is vital for Class 12 Biology, NEET, and MDCAT preparation.
You’ll learn:
1️⃣ Meaning and importance of DNA replication
2️⃣ Key enzymes — DNA helicase, primase, DNA polymerase, ligase
3️⃣ Steps: initiation → elongation → termination
4️⃣ Leading & lagging strands, Okazaki fragments
5️⃣ Semi-conservative model (Meselson & Stahl experiment)
6️⃣ Exam-focused explanation for NEET & MDCAT
This video makes molecular biology simple and easy to remember.

0:00 – Introduction to DNA Replication
0:50 – Important DNA concepts before starting replication
3:04 – Step 1: Origin of replication & Initiation
3:49 – DNA Gyrase (Topoisomerase) enzyme activity
4:37 – Helicase enzyme and DNA unwinding
5:47 – Replication fork, SSB proteins & replication bubble
8:49 – Step 2: Elongation (Leading & Lagging strands)
10:33 – Proofreading and error correction
14:16 – Step 3: Termination of DNA replication

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