肿瘤标志物CA15 3有何临床意义 王瑞芹 山西省肿瘤医院

肿瘤标志物CA15-3有何临床意义 王瑞芹 山西省肿瘤医院
A15－3是监测乳腺癌的重要抗原，存在于多种腺癌细胞中，如乳腺癌、肺腺癌、卵巢癌、胰腺癌等。对乳腺癌的相关性较高，对乳腺癌的敏感性和特异性都高于CEA、TPA。非转移性乳腺癌阳性增高30％～40％；转移性乳腺癌70％～80％增高。因此，主要用于判断乳腺癌的进展和转移、监测治疗和复发。

The clinical significance of tumor marker CA15-3
A15-3 is an important antigen for monitoring breast cancer, It is present in a variety of adenocarcinoma cells, Such as breast cancer, lung adenocarcinoma, ovarian cancer, pancreatic cancer, etc. The correlation with breast cancer was high, The sensitivity and specificity to breast cancer were higher than CEA and TPA. The positive rate of non metastatic breast cancer was 30% - 40%; 70% - 80% of metastatic breast cancer increased. So, It is mainly used to judge the progress and metastasis of breast cancer, monitor treatment and recurrence.