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Hoffmann Rearrangement and Elimination | organic chemistry
Автор: The Science Archive
Загружено: 2025-04-03
Просмотров: 15
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Mechanisms.
Instead of putting 2H on N where one H came from water, on exam could also just do proton transfer between OH and N, then use O- to expel N leaving group
Happens in Br2, OH-, H2O…turns amides into amines but with one less C (due to isocyanate that makes the C=O as leaving group)
Amine reactions
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