Exploring Leucovorin’s (Folinic Acid) Role in Autism Treatment: A Scientific Overview

In this video, Dr. Farid Din of Din Neurology explores the promising role of folinic acid (leucovorin) in treating children with Autism Spectrum Disorder (ASD)—especially those with language delays and communication difficulties. Backed by clinical research, folinic acid has shown significant improvements in speech and social engagement, particularly in children who test positive for Folate Receptor Alpha Autoantibodies (FRAAs).

We break down:

What folinic acid is and how it works in the brain

The link between cerebral folate deficiency and autism

Research evidence showing improved communication in ASD

How to identify candidates who may benefit from this treatment

📚 Reference:
Frye, R.E., Slattery, J., Delhey, L., et al. Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial. Molecular Psychiatry. 2018 Jan;23(2):247–256.
🔗 Read the full study on PubMed

Whether you're a parent, clinician, or researcher, this video offers insight into a safe, science-backed approach to supporting children with autism.

📍 Learn more about Dr. Din and our clinic: www.dinneurology.com

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