GLP-1 Agonists for Weight Loss: Nutritional Management of Common Adverse Effects

Presented by Kelly Heim, PhD+
Originally Aired: October 2024

Description: GLP-1 agonists are widely used for metabolic and weight loss applications, with an estimated 12% of U.S. adults reporting current or past use.1 Common adverse effects often limit the overall success of GLP-1 therapies. This lecture reviews the basic and clinical pharmacology of GLP-1 agonists, with a special focus on nutritional strategies for managing common adverse effects and supporting durable weight management after drug discontinuation.

Learning Objectives:

• Review the functions, indication and mechanism of action of GLP-1 agonists
• Recognize common adverse effects of GLP-1 agonists
• Discover nutritional and lifestyle interventions to help manage occasional gastrointestinal adverse effects and preserve lean body mass
• Learn how to prevent weight rebound after drug cessation

About the speaker:

Kelly C. Heim, PhD, is a Senior Consultant of Medical Affairs at Pure Encapsulations® and Founder and Senior Science Editor at Integrative Pharmacology. He received his doctoral degree in pharmacology from Geisel School of Medicine at Dartmouth College and specializes in the pharmacology of natural compounds. Dr. Heim is a published author and illustrator of various studies, scholarly reviews and book chapters. He offers complimentary learning resources on the basics of clinical pharmacology of natural products via his website, IntegrativePharmacology.com.

+Dr. Heim is an employee of Pure Encapsulations.

1. Harris E. Poll: Roughly 12% of US Adults Have Used a GLP-1 Drug, Even If Unaffordable. JAMA.2024;332(1):8. doi:10.1001/jama.2024.10333