Conversations on MS with Dr. Enrique Alvarez: August 18, 2025

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Conversations on MS with Dr. Enrique Alvarez, recorded live in Centennial, Colorado on August 18, 2025.

TOPICS ADDRESSED IN THIS SESSION:
(Please click the time to be taken to that point of the video.)

0:00 Video begins
3:38 New diagnostic criteria
6:44 Terminology: Relapses, pseudo-relapses, inflammation, progression
12:39 Stopping DMT / older age diagnosis
15:53 PML (and switching from Tysabri to a B-cell depleting therapy)
20:48 Switching from B-cell depleting therapy to Tysabri
22:38 Cancer risk and DMTs (Ocrevus/B-cell depleters, cladribine/Mavenclad)
27:24 Spinal cord lesions
29:27 Monophasic Balo’s disease
32:31 Cancers associated with Mavenclad
33:00 Committee for new diagnostic criteria
34:25 Creatine
35:31 Nervive
36:17 Remodulin
36:46 Probiotics
39:19 Osteoporosis
40:42 Vitamin D
41:55 Pregnancy and family planning
47:41 Vitamin D recommendation
49:05 Genetics and MS
51:58 Is MS more prevalent in Colorado?
54:49 Environmental risk factors, EBV or other trigger
58:04 Leg weakness, spasticity, foot drop, TENS units, walk aids
1:06:50 Brain atrophy
1:08:33 Hand tremors
1:10:49 Octave blood test
1:13:11 IRIS
1:14:42 The role of AI
1:16:40 COVID – vaccines etc.
1:23:29 UV light