A Protein is Protecting You from Chronic Disease—And You’re Shutting It Off Eating THIS Way!

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0:00 - Introduction
1:20 - Dendritic Cells & Inflammation
4:05 - Visceral Fat, Beta-Catenin, and your Health
6:52 - Visceral Fat reduces Inflammation??
9:15 - How do we preserve Beta-Catenin?
11:18 - Main Points

References
[Study 506] Macdougall CE, Wood EG, Loschko J, et al. Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets. Cell Metabolism. 2018 Mar 6;27(3):588–601.e4. doi:10.1016/j.cmet.2018.02.007

Funding/Conflicts: Mixed Funding [Public: Public support came from the Medical Research Council (MRC) (MR/L002345/1) and the Medical College of Saint Bartholomew’s Hospital Trust, both of which are affiliated with publicly funded academic institutions. Non-profit funding included multiple grants from the British Heart Foundation (FS/13/49/30421, PG/16/79/32419, FS/14/66/31293), the Marie Curie / Cascade Fellowship (CF-2013-11-003-longhi); Non-Profit: Action Against Cancer and the Hilary Craft Foundation (PS8508). Additionally, one author was supported by a studentship from Bart’s and the London School of Medicine, a non-profit academic institution.] // No direct Conflicts of Interest

[A] Fontana L, Eagon JC, Trujillo ME, Scherer PE, Klein S. Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes. 2007;56(4):1010-1013. doi:10.2337/db06-1656

[B] Beasley LE, Koster A, Newman AB, et al. Inflammation and race and gender differences in computerized tomography-measured adipose depots. Obesity (Silver Spring). 2009;17(5):1062-1069. doi:10.1038/oby.2008.627

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