Next Generation NCLEX 2026 Practice Questions - Test Prep & Review (25 Challenging Questions)

Preparing for the Next Generation NCLEX requires practicing with exam-style questions that challenge your critical thinking, prioritization, and clinical judgment skills. This video presents 25 of the most challenging NCLEX 2026 practice questions and answers with detailed rationales, making it an essential test prep and study guide for nursing students, graduates, and professionals aiming to pass the NCLEX-RN on their first attempt.

In this review, you’ll cover high-yield topics such as prioritizing assessment findings in heart failure, IM injection needle selection, warfarin and vitamin K interactions, acute asthma interventions, pediatric fluid status assessment, alcohol withdrawal recognition, colostomy care and stoma protection, DVT diagnostics, insulin administration errors, seizure safety priorities, hyperthyroidism symptoms, infection control for C. difficile, chest tube management, hypertension lifestyle modifications, myocardial infarction emergency protocols, chronic kidney disease imbalances, BPH symptoms, neutropenia precautions, and patient education for diabetes and UTI prevention
. Each question is paired with a clear rationale to help you understand the correct answer and apply nursing knowledge in real-world clinical settings.

This video is especially valuable for test-takers preparing for the Next Generation NCLEX format, which emphasizes case-based reasoning and decision-making. By practicing with these challenging questions, you’ll build confidence, sharpen your exam strategies, and reduce test-day anxiety.

If you’re committed to becoming a registered nurse in 2026, watch until the end for full explanations, subscribe for more NCLEX study guides and nursing exam prep content, share this resource with classmates and colleagues, and comment below with nursing topics you’d like to see featured in future reviews.

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