NFL WEEK 18 ALL GAME PICKS AND PREDICTIONS: Who will win this week's NFL games?

Get ready for the final and wildest weekend of the regular season! NFL Week 18 is packed with playoff-deciding matchups, division battles, and win-or-go-home drama. In this video, we break down every game on the slate, with full attention on the three matchups that will shape the postseason picture.

First, we dive into the massive NFC West showdown: San Francisco 49ers vs. Seattle Seahawks. The 49ers look to secure playoff positioning with their explosive offense, but Seattle enters desperate and motivated, fighting to claim the final NFC Wild Card spot.

Can the Seahawks’ defense slow down Christian McCaffrey and the Niners’ high-powered attack?

Next, we turn to one of the NFL’s greatest rivalries—turned Week 18 division decider. It’s Baltimore Ravens at Pittsburgh Steelers, and everything is on the line. The Ravens’ elite defense faces a resurgent Steelers offense playing its best football of the year. With the AFC North title hanging in the balance, this is must-watch football at its finest.

We also preview the winner-take-all NFC South matchup: Carolina Panthers at Tampa Bay Buccaneers. Carolina’s defense has carried them all season, but they’ll need a flawless performance to slow down Baker Mayfield and Tampa’s passing attack. The winner punches their ticket to the postseason(Tampa with some help) —while the loser heads home.

We’ll break down key players to watch, matchup advantages, betting angles, and final game picks to help you get ready for the most important weekend of the year.

If you love NFL breakdowns, weekly predictions, or playoff analysis, you’re in the right place!

Chapters:

0:21 Carolina Panthers at Tampa Bay Buccaneers (NFC South Title)
1:10 Indianapolis Colts at Houston Texans (Can the Texans win the AFC South?)
1:47 Cleveland Browns at Cincinnati Bengals (Can Myles Garrett set the Sack Record?)
2:38 New Orleans Saints at Atlanta Falcons (Can the Falcons play spoiler for the Bucs?)
3:24 Tennessee Titans at Jacksonville Jaguars (Jags need one win for the AFC South)
3:58 Seattle Seahawks at San Francisco 49ers (Best game of the week)
5:06 Arizona Cardinals at Los Angeles Rams
5:52 Dallas Cowboys at New York Giants
6:24 Kansas City Chiefs at Las Vegas Raiders
6:55 Washington Commanders at Philadelphia Eagles
7:38 Miami Dolphins at New England Patriots
8:26 Detroit Lions at Chicago Bears
9:10 Los Angeles Chargers at Denver Broncos
9:55 Week 17 Results
10:24 New York Jets at Buffalo Bills
11:00 Baltimore Ravens at Pittsburgh Steelers (AFC North Title Match)


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