Protein plasticity and evolution: The research group of Agnes Toth-Petroczy at MPI-CBG
Автор: MPI-CBG
Загружено: 2025-11-28
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Get to know the research group of Agnes Toth-Petroczy at the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) in Dresden, Germany and at the Center for Systems Biology Dresden (CSBD). The researchers in this group seek to understand protein sequence space in the light of evolution and erroneous protein production with focus on intrinsically disordered proteins regions (IDRs). They are fascinated by proteins and their robustness and plasticity towards mutations: a single mutation can result in a novel protein function or a damaged protein leading to disease.
The group mainly performs computational experiments using the vast amount of experimental data available, but also tests hypotheses experimentally, generates own data, and works closely with experimental collaborators and clinicians.
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