Je LSD naozaj také nebezpečné?

V tomto videu sa dozvieš, čo s telom robí LSD a aké využite by mohlo nájsť v psychomedicíne.

Video pripravil Peťo z BeWise
   / @petobewise  

ZDROJE:

1. Carhart-Harris, Robin L., Suresh Muthukumaraswamy, Leor Roseman, Mendel Kaelen, Wouter Droog, Kevin Murphy, Enzo Tagliazucchi, Eduardo E. Schenberg, Timothy Nest, Csaba Orban, Robert Leech, Luke T. Williams, Tim M. Williams, Mark Bolstridge, Ben Sessa, John Mcgonigle, Martin I. Sereno, David Nichols, Peter J. Hellyer, Peter Hobden, John Evans, Krish D. Singh, Richard G. Wise, H. Valerie Curran, Amanda Feilding, and David J. Nutt. "Neural Correlates of the LSD Experience Revealed by Multimodal Neuroimaging." Proceedings of the National Academy of Sciences 113.17 (2016): 4853-858.

2. Cohen, M. M., M. J. Marinello, and N. Back. "Chromosomal Damage in Human Leukocytes Induced by Lysergic Acid Diethylamide." Science 155.3768 (1967): 1417-419.

3. Corey, Margaret J., J. C. Andrews, M.josephine Mcleod, J. Ross Maclean, and W. E. Wilby. "Chromosome Studies on Patients (in Vivo) and Cells (in Vitro) Treated with Lysergic Acid Diethylamide." New England Journal of Medicine 282.17 (1970): 939-43.

4. Das Saibal, Preeti Barnwal, Anand Ramasamy, Sumalya Sen and Somnath Mondal, „Lysergic acid diethylamide: a drug of ‘use’?“ Therapeutic Advances in Psychopharmacology (2016), 6(3) 214–228.

5. Dishotsky, N. I., W. D. Loughman, R. E. Mogar, and W. R. Lipscomb. "LSD and Genetic Damage." Science 172.3982 (1971): 431-40.

6. Ditan, Theodor. "Psychedelics Not Linked to Mental Health Problems or Suicidal Behavior."Scribd. (2017)

7. Dolder, Patrick C., Yasmin Schmid, Andrea E. Steuer, Thomas Kraemer, Katharina M. Rentsch, Felix Hammann, and Matthias E. Liechti. "Pharmacokinetics and Pharmacodynamics of Lysergic Acid Diethylamide in Healthy Subjects." Clinical Pharmacokinetics (2017): 13

8. Gable, Robert S. "Toward a Comparative Overview of Dependence Potential and Acute Toxicity of Psychoactive Substances Used Nonmedically." The American Journal of Drug and Alcohol Abuse 19.3 (1993): 263-81.

9. Halberstadt, Adam L. "Recent Advances in the Neuropsychopharmacology of Serotonergic Hallucinogens." Behavioural Brain Research 277 (2015): 99-120.

10. Hendricks, Peter S., Christopher B. Thorne, C. Brendan Clark, David W. Coombs, and Matthew W. Johnson. "Classic Psychedelic Use Is Associated with Reduced Psychological Distress and Suicidality in the United States Adult Population." Journal of Psychopharmacology 29.3 (2015): 280-88.

11. Hofmann, „How LSD Originated“ Journal of Psychoactive Drugs (1979): 11-1-2

12. Irwin, S., and J. Egozcue. "Chromosomal Abnormalities in Leukocytes from LSD-25 Users."Science 157.3786 (1967): 313-14.

13. Martin, David A., Danuta Marona-Lewicka, David E. Nichols, and Charles D. Nichols. "Chronic LSD Alters Gene Expression Profiles in the MPFC Relevant to Schizophrenia."Neuropharmacology 83 (2014): 1-8.

14. Rafael G. dos Santos, Flávia L. Osório, José Alexandre S. Crippa, Jordi Riba, Antônio W. Zuardi and Jaime E. C. Hallak, „Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years“ Therapeutic Advances in Psychopharmacology (2016), 6(3) 193–213

15. Wacker, D., S. Wang, J.d. Mccorvy, R.m. Betz, A.j. Venkatakrishnan, A. Levit, K. Lansu, Z.l. Schools, T. Che, D.e. Nichols, B.k. Shoichet, R.o. Dror, and B.l. Roth. "Crystal Structure of the LSD-bound 5-HT2B Receptor." The Cell (2017): 22-9