Male Reproductive System | Spermatogenesis

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Ninja Nerds!
In this reproductive physiology lecture, Professor Zach Murphy walks you through the detailed process of spermatogenesis, the production and maturation of spermatozoa within the seminiferous tubules of the testes. This lecture outlines anatomical organization and hormonal regulation that ensure continuous sperm production in the male reproductive system.

We begin by exploring the roles of the Sertoli and Leydig cells, including their response to FSH and LH. You’ll learn how LH stimulates testosterone production from Leydig cells, while FSH acts on Sertoli cells to promote sperm development and maintain the blood-testis barrier. The lecture breaks down the stages of spermatogenesis—from spermatogonia to primary and secondary spermatocytes, spermatids, and finally mature spermatozoa—highlighting the critical meiotic divisions and cellular remodeling that occur along the way.

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