Cell Migration Seminar #1: Jeff Fredberg

Geometry of cell jamming: new biology, surprising physics, and useful ideas about epithelial layers.

References discussed during the seminar:

Park et al, Nature Materials 2015. "Unjamming and cell shape in the asthmatic airway epithelium." https://www.ncbi.nlm.nih.gov/pubmed/2...

Atia et al, Nature Physics 2018. "Geometric constraints during epithelial jamming" https://www.nature.com/articles/s4156...

Mitchel, et al, BioRxiv 2019. "The unjamming transition is distinct from the epithelial-to-mesenchymal transition". https://www.biorxiv.org/content/10.11...

Kang*, Ferruzzi*, et al, BioRxiv 2020. "Tumor invasion as non-equilibrium phase separation." https://www.biorxiv.org/content/10.11...

Han, et al, Nature Physics 2019. "Cell swelling, softening and invasion in a three-dimensional breast cancer model". https://www.nature.com/articles/s4156...


And some additional work which may be of interest:

Park, et al, Journal of Cell Science 2016 (review). "Collective migration and cell jamming in asthma, cancer and development." https://www.ncbi.nlm.nih.gov/pubmed/2...

O'Sullivan, et al, Frontiers in Cell & Developmental Biology 2020. "Irradiation Induces Epithelial Cell Unjamming." https://www.ncbi.nlm.nih.gov/pubmed/3...