Lupus & Sjögren’s: What Happens to Your Body During a Lupus vs Sjögren’s FLARE?

Lupus & Sjögren’s flare symptoms can feel unpredictable and overwhelming. If you’ve ever wondered what actually happens inside your body during a Lupus vs Sjögren’s flare, this breakdown will help you finally make sense of those sudden waves of fatigue, pain, and inflammation.

🌡️ What Changes Inside Your Body During a Flare?
When a lupus flare hits, your immune system shifts into attack mode—often targeting joints, skin, and even internal organs. That’s why you might notice sudden joint swelling, chest pain, or the classic Lupus fatigue that feels like “my body hit a wall overnight,” as I mention in the video. During a Sjögren’s flare, the immune system focuses more on moisture-producing glands, leading to intense dry eyes, dry mouth, and that burning, sandpaper-like irritation that so many viewers write to me about.
🔥 Lupus vs Sjögren’s Flares: How They Feel Different
If you’re trying to figure out “Is this a lupus flare or a Sjögren’s flare?” pay attention to how symptoms cluster. Lupus flares often bring whole-body systemic inflammation—fevers, rashes, body aches—while Sjögren’s flares may start subtly with gland swelling, dryness spikes, or neuropathy flares. Many patients tell me the dryness feels “internal,” almost like the body is dehydrating itself from the inside out.
🧠 Why These Autoimmune Flares Come and Go
Both conditions can flare due to stress, infection, hormones, or even weather changes. In the video, I explain how immune dysregulation builds quietly for days before symptoms explode. Understanding these early signals can help you intervene sooner—something many people search for as “How do I know if a flare is starting?”
💛 Managing Flares With Confidence
This video is for anyone living with lupus, Sjögren’s syndrome, connective tissue disease, UCTD, or supporting a loved one through chronic illness. My goal is to help you connect the dots between what you feel and what your body is actually doing so you can navigate each flare with more confidence and less fear.

▶️ RELATED VIDEOS
Want to get ahead of symptoms before they ramp up? Watch this next: “Early Signs of a Lupus Flare You Should Never Ignore.”
Struggling with severe dryness or neuropathy? Try: “Sjögren’s Syndrome: How to Manage Dryness Flares Naturally.”
If this deep dive on Lupus & Sjögren’s flare patterns helps you, stick around and keep learning—your body will thank you.




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