Can Cell Therapy Reverse Hearing Loss? Development of Lineage Cell Therapeutics ReSonance™ Program

Can cell therapy revolutionize hearing loss treatment? In this follow-up discussion, Brian Culley, CEO of Lineage Cell Therapeutics, shares the latest updates on the ReSonance™ (ANP1) program, a pioneering preclinical study exploring auditory neuron cell transplantation. Culley explains how lab-grown auditory neurons are being delivered to the inner ear to potentially restore damaged auditory pathways—a groundbreaking approach that could even complement existing treatments.

In this conversation, Culley sheds light on the preclinical results, including the successful delivery of auditory neurons in animal models, and discusses the challenges and opportunities ahead as Lineage prepares for clinical trials.

The discussion also touches on the broader implications of cell therapy and its potential integration into hearing care solutions.

For more information on the company's ReSonance program, visit: https://lineagecell.com/products-pipe...

***Interested in the latest in cell therapy and other cutting-edge hearing loss treatments under development? You won't want to miss out on the 2025 Hearing Therapeutics Virtual Summit.
Taking place from February 4-5. Learn more and register here:
https://www.accelevents.com/e/Hearing...

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TIMESTAMPS
00:00 Introduction
00:41 Background - Brian Culley, Lineage Cell Therapeutics CEO
02:12 Resonance study
03:42 Preclinical study vs. trial
05:49 How might cell therapy improve patient outcomes?
07:20 Applications outside of hearing
09:04 Challenges of cell therapy for hearing
10:26 Partnership with University of Michigan
12:43 Where might cell therapy fit alongside other hearing loss treatments?