Heparin-Induced Thrombocytopenia (HIT) | A Comprehensive Explanation

Heparin-Induced Thrombocytopenia (HIT) | A Comprehensive Explanation...There are two types of HIT: HIT-type I and HIT-II.

Heparin is an anticoagulant that stimulates antithrombin III (ATIII) which then inhibits coagulation factors VII, IX, X, XI, XII, as well as thrombin. This leads to prevention of thrombus formation (anticoagulation)...Heparin is used for ICU anticoagulation...Adverse effects of heparin includes bleeding, Heparin-induced thrombocytopenia (HIT), and osteoporosis.
Heparin | The blood 🩸 thinner | The Anticoagulant | Pharmacology | Hematology.


Anticoaulants are chemicals that inhibit blood coagulation (secondary hemostasis).

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Vitamin K Deficiency | Hemorrhagic Disease of the Newborn or Vitamin K dependent bleeding (VKDB) is a bleeding disorder that occurs due to deficiency of vitamin K.
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Coagulation Tests (PT, aPTT, TT, Fibrinogen, Mixing Studies,..etc).
The coagulation factors are divided into 3 coagulation groups | Fibrinogen group, Prothrombin group, and Contact Group..

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Platelet count is one of the lab tests used by a doctor or a hematologist to assess whether your platelet number is normal, low (thrombocytopenia) or high (thrombocytosis).

Bleeding 🩸 time (BT) is another test for platelet function.

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