Host Defense Infection

N 717 Advanced Pathophysiology – Lecture 2: Host Defense Mechanisms

In this graduate-level nursing lecture, we break down how the human body defends itself against infection and disease. This session covers the essentials of host defense mechanisms and links them directly to clinical practice for nurse practitioners.

🔑 Key Topics:

Innate vs. adaptive immunity

Major immune cells and their functions

Bacterial, viral, and fungal infection pathways

Allergy, hypersensitivity, and autoimmunity

Sepsis, septic shock, and long COVID

Pediatric considerations: immune immaturity, vaccine-preventable illnesses

Geriatric considerations: immunosenescence and atypical infection presentations

📘 Required Reading: Harrison’s Principles of Internal Medicine, 21e – Ch. 119–123, S11

🎯 Designed for:

Nurse Practitioner students (FNP, PMHNP, CRNA)

Graduate nursing students preparing for boards and advanced practice

Clinicians seeking a stronger foundation in pathophysiology and immunity

This lecture is part of NURS 717: Advanced Pathophysiology for Nursing Practice at Hunter-Bellevue School of Nursing.

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