Chicago White Sox vs Minnesota Twins Predictions Today | Wednesday MLB Picks For 4/23/25

If you are looking for MLB picks, predictions and best bets for today's Chicago White Sox vs Minnesota Twins matchup, we have you covered! Our MLB handicapping experts discuss the spread and total from a sports betting perspective, sharing their picks and predictions vs the current odds.

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Chicago White Sox vs. Minnesota Twins – April 23, 2025

The Chicago White Sox (5–18) continue their series against the Minnesota Twins (8–15) at Target Field in Minneapolis.​

Game Details:

Date: Wednesday, April 23, 2025
Time: 7:40 PM ET
Location: Target Field, Minneapolis, MN​

TV Broadcast:

White Sox: Chicago Sports Network (CHSN)
Twins: TWTV

Betting Odds:

Moneyline: Twins -265, White Sox +218
Over/Under: 8.5 runs

Starting Pitchers:

White Sox: Bryse Wilson (0–0, 4.50 ERA)
Twins: David Festa (0–0, 0.00 ERA)​

Team Hashtags:

Chicago White Sox: #ChangeTheGame
Minnesota Twins: #MNTwins​

Interesting Facts:

The Twins are on a three-game home winning streak and lead the season series against the White Sox 3–1.

Twins' prospect David Festa is making his MLB debut; he has recorded 10 strikeouts in the minors this season.

White Sox outfielder Andrew Benintendi leads the team with four home runs and eight RBIs, batting .241.

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