Talquetamab Side Effects: Managing Taste Loss, Hair & Nail Changes in Myeloma | Myeloma Made Simple

New bispecific antibodies like TALVEY® (talquetamab-tgvs) unlock a powerful way to attack multiple myeloma via the GPRC5D target—but they can cause unique side effects. In this Myeloma Made Simple episode, Dr. Joseph Mikhael, Chief Medical Officer of the International Myeloma Foundation, explains how to recognize and manage these issues, so you can keep your quality of life high.

Topics covered in this video:
0:00 – Intro
1:44 – Why talquetamab is a game-changer in relapsed multiple myeloma
2:13 – Common bispecific side effects (CRS, neurotoxicity, infections)
2:40 – Unique GPRC5D side effects overview
2:59 – Taste changes: tips for keeping meals enjoyable
3:33 – Nail thinning & loss: protective care strategies
3:57 – Hair thinning: moisturizing & styling pointers
4:15 – Palmar/plantar rash: prevention & treatment
4:45 – Dosing adjustments to reduce side‐effect intensity
5:16 – Key takeaways & how to talk to your care team

Subscribe for weekly updates on myeloma research, treatment, and patient support. Have a question that needs more personalized support? Call us! We’re here for you. The IMF’s InfoLine is available to answer your myeloma-related questions and concerns. Call us at 1-818-487-7455, email us at [email protected], or schedule your call at a time that works best for you at: https://www.myeloma.org/infoline.

Supported by an educational grant from Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC
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Improving Lives | Finding the Cure

Founded in 1990, the International Myeloma Foundation (IMF) is the first and largest organization focusing specifically on multiple myeloma. The IMF’s reach extends to more than 525,000 members in 140 countries worldwide. The IMF is dedicated to improving the quality of lives of myeloma patients while working toward prevention and a cure through our four founding principles: Research, Education, Support, and Advocacy.

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The International Myeloma Foundation is committed to accessibility for all. That’s why all English-language videos uploaded to our YouTube channel feature human-transcribed closed captioning. This ensures more accurate captions for viewers who are Deaf or hard of hearing and improves the quality of automatic translations into other languages for our global audience.