The Neuroscience of Psychedelics Explained: How LSD, Psilocybin, MDMA & Ketamine Affect the Brain

The Neuroscience of Psychedelics Explained: How LSD, Psilocybin, MDMA & Ketamine Affect the Brain

Trauma Therapy Training at Academy of Therapy Wisdom continues to explore cutting-edge approaches to healing by examining the basic neuroscience of psychedelics and their effects on the brain. In this training, we break down how substances like LSD, psilocybin, MDMA, ketamine, mescaline, and DMT interact with the nervous system and why they hold such powerful therapeutic potential.

This session is part of Academy of Therapy Wisdom Continuing Education Mental Health, offering therapists a clear, research-based understanding of how psychedelics influence serotonin receptors, brain networks, emotional processing, and neuroplasticity — all critical knowledge for ethical psychedelic integration work.

You’ll learn how classic psychedelics activate the 5-HT2A receptor, how MDMA uniquely supports empathy and bonding in trauma therapy, and why ketamine’s NMDA receptor activity makes it distinct from other psychedelic medicines. We also explore mystical experiences, default mode network changes, emotional processing in the amygdala, and the concept of an inner healing intelligence.

Join DaeEss 1Drea Pennington Wasio, MD, for a FREE 60-minute webinar: Psychedelic Therapy at the Crossroads of Neuroscience and Spirituality: https://therapywisdom.com/psychedelic...

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