Metabolic Networks
Автор: Dr. Ashish Runthala
Загружено: 2025-05-19
Просмотров: 330
A metabolic network in a biological cell system represents the complex web of biochemical reactions through which cells convert nutrients into energy and essential biomolecules. These networks, composed of enzymes, metabolites, and pathways, are categorized into catabolic and anabolic processes that maintain cellular homeostasis and adapt to environmental changes. Metabolic analysis plays a vital role in studying these systems by quantifying metabolite levels, enzyme activities, and flux distributions. It integrates multi-omics data to provide a holistic understanding of cellular metabolism under different physiological or pathological states. Regulatory mechanisms, including genetic control, allosteric modulation, and signaling pathways, dynamically govern these networks. Computational models, supported by metabolic analysis, help simulate metabolic behavior, predict outcomes of perturbations, and guide metabolic engineering or therapeutic strategies. This integrated approach is essential for understanding disease mechanisms, enhancing bioproduction, and advancing systems biology.
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