Why IM Progesterone is Preferred in Frozen Embryo Transfers: A Look at the Science

Struggling to understand why your doctor recommends intramuscular progesterone shots for frozen embryo transfer cycles? You’re not alone and knowing the science behind it could be the key to increasing your chances of a successful pregnancy. In this video, I explain why IM progesterone is often preferred over other forms, especially in programmed FET cycles, and what the latest research says about its impact on live birth and miscarriage rates.

As a double-board-certified OBGYN and reproductive endocrinologist with over 20 years of experience, I’ve seen firsthand how the right type of progesterone support can make a major difference. Whether you're preparing for your first frozen embryo transfer or looking for clarity on your treatment plan, this video will help you feel informed and empowered for your next steps.

In this video, you’ll learn:
• Why progesterone is essential for implantation and early pregnancy
• The differences between programmed and natural FET protocols
• All available progesterone options and why some work better than others
• Key findings from a landmark 2021 randomized controlled trial
• How IM progesterone improves success rates in FET cycles
• What to ask your doctor when choosing a progesterone protocol

If you’re navigating IVF or supporting someone who is, this video can be a valuable tool. Share it with anyone going through fertility treatment it could help them make a more confident and informed decision.


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ABOUT : Lora Shahine, MD, is a double board certified reproductive endocrinologist and OBGYN currently practicing at Pacific NW Fertility in Seattle, WA. Originally from North Carolina, Dr. Shahine graduated with a Bachelor of Science in biology from Georgetown University in Washington, DC, and completed her training in medical school at Wake Forest University School of Medicine, residency in obstetrics and gynecology at the University of California at San Francisco, and fellowship in reproductive endocrinology and infertility at Stanford University.
As Clinical Assistant Professor at the University of Washington and Director of the Center of Recurrent Pregnancy Loss at Pacific NW Fertility, she is committed to providing excellence in patient care, teaching the next generation of women’s healthcare providers, and continuing research in the fields of fertility and recurrent miscarriage. She has published over 75 peer-reviewed research projects and is an active member of the American Society of Reproductive Medicine, Seattle Gynecology Society, and the Babyquest Fertility Grant organization. Dr. Shahine is an accomplished author including 'Planting the Seeds of Pregnancy: An Integrative Approach to Fertility Care' and best-selling book, 'Not Broken: An Approachable Guide to Miscarriage and Recurrent Pregnancy Loss.'
Whether through her research, books, lectures, or active social media presense Dr. Shahine is passionate about educating on reproductive health and supporting the feritlity community.

DISCLAIMER: The content contained herein is provided for informational and/or entertainment purposes only and not intended as a substitute for advice provided by a healthcare professional. Use the provided information at your own risk. If you have or suspect that you have a medical problem, please contact your health care provider.



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