#148

Is tetrahexyldecyl ascorbate (aka. THD ascorbate) a more stable, more exciting form of vitamin C, or just another quirky chemical cousin? We unpack the science, separate facts from marketing fluff, and reveal what this ingredient really does for your skin.

Timestamps
00:00 | Is THD Ascorbate a Good Antioxidant?
00:41 | Why People Are Curious About Vitamin C Derivatives
01:07 | How THD Compares to Ascorbic Acid in ORAC Assay
03:05 | Why THD May Be 30,000x Weaker Than Ascorbic Acid
05:10 | THD vs Acetyl Zingerone in Antioxidant Efficiency
06:17 | Stability Problems of THD Under Oxidative Stress
08:17 | Does THD Have Clinical Benefits Despite Weak Data?
09:15 | Anti-aging & Hyperpigmentation Study with THD
14:14 | Does Higher THD % Improve Pigmentation Results?
16:36 | Clinical Trial with 30% THD During Summer Exposure

Products Discussed this 2025 Podcast Season
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Product Shoutout:
Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/produc...

Enrichment Content:
EP144: Is 3-o-ethyl ascorbic acid a worthy vitamin C derivative?
   • #144) Is 3-o-ethyl ascorbic acid a worthy ...  

From the Blog: Which Vitamin C Derivative is Best for My Skin
https://chemistconfessions.com/blogs/...

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