Obesidade: Genética ou Estilo de vida?

Seja membro deste canal e apoie a divulgação científica brasileira:
   / @nuncavi1cientista  

00:00 - Introdução
00:17 - o que é obesidade
04:51 - regulação da fome no cérebro
09:09 - regulação da fome fora do cérebro
16:45 - tipos de obesidade
24:48 - incidência dos tipos de obesidade

Roteiro: Ana Bonassa
Produção: Ana Bonassa
Edição: Laís Maurelli
Design da miniatura: Andre Charneski
Legendas: Beatriz Pinheiro

Busca de conteúdos:
www.nv1c.com

Referências:
Updates on Monogenic Obesity in a Multifactorial Disease. Obes Surg. 2019. doi: 10.1007/s11695-019-04200-z.
Genetics of Obesity: What We Have Learned Over Decades of Research. Obesity (Silver Spring). 2021. doi: 10.1002/oby.23116.
Sequencing methods, functional characterization, prevalence, and penetrance of rare coding mutations in panels of monogenic obesity genes from the leptin-melanocortin pathway: A systematic review. Obes Rev. 2024. doi: 10.1111/obr.13754.
Current Treatments for Patients with Genetic Obesity. J Clin Res Pediatr Endocrinol. 2023. doi: 10.4274/jcrpe.galenos.2023.2023-3-2.
New advances in the genetics of early onset obesity. Int J Obes (Lond). 2005. doi: 10.1038/sj.ijo.0803056.
Monogenic human obesity syndromes. Handb Clin Neurol. 2021. doi: 10.1016/B978-0-12-820683-6.00022-1.
Monogenic human obesity. Front Horm Res. 2008. doi: 10.1159/000115333.
Monogenic Obesity Syndromes Provide Insights Into the Hypothalamic Regulation of Appetite and Associated Behaviors. Biol Psychiatry. 2022. doi: 10.1016/j.biopsych.2022.01.018.
Differentiating monogenic and syndromic obesities from polygenic obesity: Assessment, diagnosis, and management. Obes Pillars. 2024. doi: 10.1016/j.obpill.2024.100110.
Management of Monogenic and Syndromic Obesity. Gastroenterol Clin North Am. 2023. doi: 10.1016/j.gtc.2023.08.005.
https://www.cfn.org.br/index.php/noti...
Melanocortin-4 receptor-regulated energy homeostasis. Nat Neurosci. 2016. doi: 10.1038/nn.4202.
Implications of proopiomelanocortin (POMC) mutations in humans: the POMC deficiency syndrome. Trends Endocrinol Metab. 2000. doi: 10.1016/s1043-2760(99)00213-1.
Genetics of Obesity in Humans: A Clinical Review. Int J Mol Sci. 2022. doi: 10.3390/ijms231911005.
Neuropeptide Y, alpha-melanocyte-stimulating hormone, and monoamines in food intake regulation. Nutrition. 2005. doi: 10.1016/j.nut.2004.06.021.
Medical semiology of patients with monogenic obesity: A systematic review. Obes Rev. 2024. doi: 10.1111/obr.13797.
Genetics and epigenetics in obesity. Metabolism. 2019. doi: 10.1016/j.metabol.2018.10.007.
Central nervous system control of food intake. Nature. 2000. doi: 10.1038/35007534.
Molecular genetics of human obesity: A comprehensive review. C R Biol. 2017. doi: 10.1016/j.crvi.2016.11.007.
Feasibility, safety, and efficacy of dietary or lifestyle interventions for hypothalamic obesity: A systematic review. Clin Nutr. 2024. doi: 10.1016/j.clnu.2024.05.028.

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