GET UP | 49ers will win the NFC West! - Rex Ryan on Brock Purdy DESTROY Colts defense 48-27 on MNF

Pardon the Interruption | Steelers are team that looks best in NFL, 49ers will win NFC West - Wilbon

FIRST TAKE | 49ers are NFL's best team vs 6 Pro Bowlers - Stephen A. on Brock Purdy sink Colts 48-27

San Francisco 49ers vs Indianapolis Colts Game Highlights | 2025 NFL Season Week 16

49ers beat Colts thanks to an EXCEPTIONAL Purdy, Fair to blame Ravens’ struggles on Harbaugh? | FTF

"Brock Purdy is too GOOD"- Pat McAfee reacts to Brock Purdy’s 5-TD powers 49ers past Colts 48-27

Jeff Saturday thinks DK Metcalf's suspension is 'gonne be a problem' 👀 | Get Up

San Francisco 49ers offense on fire ahead of pivotal stretch | Pro Football Talk | NFL on NBC

Colin Cowherd & Nick Wright DEBATE NFL playoff predictions, Bills SB? Chiefs rebuild | THE HERD

Will the 49ers make it to the SUPER BOWL? 🏆 'It's set up FOR THEM!' - Dan Graziano | Get Up

The Prince makes the climb, Josh Allen drops, Who will reach the top of Mahomes Mountain? | FTF

Who's on Mad Dog's NICE LIST this Christmas? 🎄 'This has to be A JOKE!' - Jeff Saturday | First Take

NFL LIVE | Marcus Spears reacts to Brock Purdy fires 5-TD, 295-Yds lead 49ers defeat Colts 48-27

49ers vs. Colts Reaction 🍿 Purdy throws 5 TDs as San Fran eyes 1 seed | SC with SVP

FIRST TAKE | 49ers are a nightmare for the NFC title - Stephen A. reacts to Niners DOMINATE Colts

49ers are SCARIEST team in NFC right now? - Ryan Clark breakdown 49ers 48-27 win over Colts

NFL LIVE | CMC & George Kittle is Best Offensibe Duo in NFL - Swagu on 49ers def. Colts 48-27

ESPN breaks down NFL Power Rankings in Wk 17: Seahawks new number 1, Bears crack top 5, Broncos drop

Dan Patrick Recaps 49ers 48-27 Win Over The Colts | 12/23/25

49ers QB Brock Purdy powers team with five TDs in dominant Week 16 win vs. Colts | NBC Sports BA

NFL LIVE | Brock Purdy is the most CLUTCH QB! - Swagu impress 49ers destroyed Colts 48-27 in Week 16