Multiple Sclerosis Research Outcomes

A discussion of multiple sclerosis research outcomes such as MRI findings, serum neurofilament light chain, ocular computed tomography, EDSS, MS functional composite, and others.

Interrater variability of EDSS: https://pubmed.ncbi.nlm.nih.gov/1565242/ Petition: https://chng.it/fPLHBTbptS
Multiple sclerosis is one disease: https://pubmed.ncbi.nlm.nih.gov/35714...
Comparison of Disease Activity in SPMS and PPMS in the Context of Multicenter Clinical Trials: https://journals.plos.org/plosone/art...
Early Clinical Features, Time to Secondary Progression, and Disability Milestones in Polish Multiple Sclerosis Patients: https://www.researchgate.net/figure/D... light chain:https://my.clevelandclinic.org/depart...
Outcome Measures in Clinical Trials for Multiple Sclerosis: https://www.ncbi.nlm.nih.gov/pmc/arti...



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Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research.

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he video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual's medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.