AI for Longevity: Georg Fuellen on Interventional Data, Synergy Discovery & Generative AI at LSD25

At Longevity Summit Dublin 2025, Professor Georg Fuellen (University Medical Center Rostock, IBIMA) explores how generative AI is reshaping the future of longevity research.

From the pitfalls of observational data to the promise of interventional trials, Fuellen shows how AI pipelines, synergy databases, and bioinformatics protocols are accelerating discoveries in aging biology. His talk introduces:

Why relying on observational epigenetic clocks can mislead anti-aging interventions.

How interventional datasets reveal real causal effects on lifespan.

The potential of Holy Bio MCP and agentic AI to combine databases, run protein alignments, and predict synergistic interventions.

Benchmarking large language models (LLMs) for personalized health advice.

Using AI across the full scientific value chain—from idea generation to data analytics and publication drafts.

This session highlights the next frontier in AI-powered longevity science: rigorous, interpretable, and intervention-driven insights that move us closer to extending healthspan and lifespan responsibly.

Chapters

00:00 – Introduction to Georg Fuellen
01:00 – Observational vs. Interventional Data in Aging
05:00 – Nutraceuticals, epigenetic clocks & pitfalls
07:00 – The rise of interventional datasets
09:00 – AI pipelines for longevity predictions
11:00 – Generative AI for grant writing & science projects
13:00 – Holy Bio MCP: multi-server bioinformatics federation
15:00 – Benchmarking AI in health recommendations
17:00 – Synergy discovery in longevity interventions
18:30 – Risks of AI hallucination vs. unchecked outputs
20:00 – Closing reflections & Q&A

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