How Exercise Reverses Artery Plaque | Latest Research

Dr. Elise Brown explains the latest research on how exercise reverses artery plaque. Arterial plaque is a hard substance that is an accumulation of fats, cholesterol, and other components. If the plaque ruptures, this could lead to a heart attack or stroke. Exercise can reduce the lipid content in the plaque, which makes the plaques more stable and less likely to rupture. Different exercise programs that have successfully reduced plaque in coronary artery disease are discussed.

Exercise education playlist:    • Exercise Education  

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Timecodes:
0:27 - Physical activity decreases risk of atherosclerosis
0:42 - What is artery plaque?
1:25 - Exercise reduces arterial plaque
1:50 - Research on exercise and plaque in coronary artery disease
3:18 - Exercise and lipid content in plaques
3:43 - Aerobic fitness and lipid content in plaques
4:06 - Need for research in women
4:18 - Exercise risk in coronary artery disease

Sources:

1. Palmefors, H., DuttaRoy, S., Rundqvist, B., & Börjesson, M. (2014). The effect of physical activity or exercise on key biomarkers in atherosclerosis–a systematic review. Atherosclerosis, 235(1), 150-161.
2. Guseh, J. S., & Jang, I. K. (2022). Exercise Intensity and Coronary Plaque Composition: Is Harder, Better, Faster, Stronger?. Journal of the American Heart Association, 11(10), e025991.
3. Vesterbekkmo EK, Madssen E, Aamot Aksetøy I-L, Follestad T, Nilsen HO, Hegbom K, Wisløff U, Wiseth R. CENIT (impact of cardiac exercise training on lipid content in coronary atheromatous plaques evaluated by near-infrared spectroscopy): a randomized trial. J Am Heart Assoc. 2022;11:e024705. doi: 10.1161/JAHA.121.024705
4. Knuuti J, Wijns W, Saraste A, Capodanno D, Barbato E, Funck-Brentano C, Prescott E, Storey RF, Deaton C, Cuisset T, Agewall S, Dickstein K, Edvardsen T, Escaned J, Gersh BJ, Svitil P, Gilard M, Hasdai D, Hatala R, Mahfoud F, Masip J, Muneretto C, Valgimigli M, Achenbach S, Bax JJ; ESC Scientific Document Group. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes. Eur Heart J. 2020 Jan 14;41(3):407-477. doi: 10.1093/eurheartj/ehz425. Erratum in: Eur Heart J. 2020 Nov 21;41(44):4242. doi: 10.1093/eurheartj/ehz825. PMID: 31504439.

Images:
1. Atherosclerotic plaque. CC. Npatchett, CC BY-SA 4.0 https://creativecommons.org/licenses/..., via Wikimedia Commons
2. CC. Lipid content plaque. Blausen.com staff courtesy of Oregon State University, CC BY-SA 2.0 https://creativecommons.org/licenses/..., via Wikimedia Commons
3. CC. Vo2max test. Fretamales, CC BY-SA 3.0 https://creativecommons.org/licenses/..., via Wikimedia Commons

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