Unlock your genetics: COMT's powerful impact on ADHD dopamine

** Ask me a question: https://www.quora.com/profile/Rayne-D...

In this video, we'll be discussing the COMT gene and how it affects ADHD. We'll explore the mystery behind this phenomenon, and how you can take advantage of it to better manage your ADHD.

** Chapters in this video:
00:00 Intro
00:52 What is Catechol-O-methyltransferase (COMT)?
01:39 Other names for COMT categories
01:50 What does it mean to be Val/val, val/met, or met/met in COMT?
02:23 How does each category change you dopamine and norepinephrine levels?
04:23 How does being Val/Val in COMT impact ADHD medications?
5:40 Benefits of getting pharmacogenomic testing

** More on COMT:
The COMT (catechol-O-methyltransferase) gene encodes the enzyme COMT, which is involved in the metabolism of neurotransmitters such as dopamine, norepinephrine, and epinephrine. A mutation in the COMT gene can affect the activity of the COMT enzyme and, in turn, impact neurotransmitter levels and functioning in the brain.

One of the most well-known COMT gene mutations is the Val158Met polymorphism, which affects the activity of the COMT enzyme. The Val allele is associated with higher COMT activity, leading to faster breakdown of dopamine in the prefrontal cortex. The Met allele, on the other hand, is associated with lower COMT activity, leading to slower breakdown of dopamine.

This difference in dopamine metabolism can have implications for cognitive and emotional functioning. Individuals with the Val allele may have better cognitive flexibility, working memory, and attention, but may also be more prone to anxiety and stress-related disorders. Individuals with the Met allele may have poorer cognitive flexibility, working memory, and attention, but may also be more resilient to stress.

It's important to note that the COMT gene is just one of many genes involved in complex traits like cognition and emotion, and that the effects of a single gene on behavior are likely to be small. Additionally, the effects of the COMT gene may interact with other genetic and environmental factors to influence an individual's traits and outcomes. Therefore, genetic testing for the COMT gene mutation should be interpreted with caution, and in the context of other factors.

DISCLAIMER: The information, including but not limited to, text, graphics, images and other material contained on this content are for informational purposes only. No material in this content is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read in this content.

#maskingautism #pharmacogenomics #pgx #rethinkadhd #precisionmedicine #ADHDandproductivityhacks #ADHDandfocustechniques #ADHDawarenessandeducation #ADHDresourcesandtools #ADHDcoachingandtherapy #ADHDandtimemanagement #UnderstandingADHDmedication #ADHDsupportgroups #CopingwithADHD #ADHDandorganization #ParentingachildwithADHD #ADHDnaturalremedies #psychiatrist #ManagingADHDsymptoms #ADHDstrategiesforstudents #ADHDtipsforadults #blackdoctor