HPLC Tips Peak Tailing

Unfortunately, peaks tail in HPLC. We don’t want them to tail. In theory we like to think of peaks as Gaussian shaped and perfectly symmetrical, but in reality just about everything in chromatography has a slight tail on it - about a 5% tail.

This is a major issue that we have to deal with. That’s why I think a lot about how to reduce peak tailing in HPLC.

What causes peak tailing in HPLC?

Read the blog here: https://axionlabs.com/chromatography-...

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