The Schizophrenia Puzzle is Solvable | W. Gordon Frankle, MD

There’s a care model for schizophrenia that actually works—why isn’t it everywhere?

On this episode, W. Gordon Frankle, MD, MBA, Vice Chair of Psychiatry at NYU Langone Health, shares how his team in Brooklyn is building a new model for treating serious mental illness—one rooted in long-term, relationship-driven, team-based care. From wraparound services to precision psychiatry, this conversation explores what happens when you bring humanity, structure, and innovation to a population too often left behind.

Dr. Frankle also discusses:
• The first novel schizophrenia drug in over 50 years (Cobenfy)
• Why clozapine is underused—and how that may finally change
• The potential of brain imaging and biomarkers in psychiatric treatment
• What a real community mental health system looks like
• Why trust, not just treatment, is essential for recovery

🔍 Topics Covered::
00:30 Introduction
01:00 Dr. Frankle’s Current Work
01:38 Advancements in Schizophrenia Research
02:59 Challenges and New Treatments in Schizophrenia
05:32 Precision Medicine in Psychiatry
06:29 PET Scans and Brain Energetics
10:16 Barriers to Effective Treatment
12:21 Clozapine and Treatment Access
14:08 Wraparound Services and Community Care
15:16 Early Screening and Public Health Interventions
19:02 Mandated Treatment and Patient Engagement
30:38 Homelessness and Mental Health
35:24 Future Directions in Schizophrenia Treatment
38:39 Conclusion

📚 Related Resources:
W. Gordon Frankle, MD, MBA - https://nyulangone.org/doctors/146747...
Schizophrenia care at NYU Langone - https://nyulangone.org/conditions/sch...
NYU Langone Hospital—Brooklyn - https://nyulangone.org/locations/nyu-...
3 Things to Know About Cobenfy (Yale Medicine) - https://www.yalemedicine.org/news/3-t...

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#schizophrenia #MentalHealth #WraparoundCare #CommunityPsychiatry #Clozapine #Cobenfy #SeriousMentalIllness #PrecisionPsychiatry #NYULangone #InsightsOnPsychiatry