Genome Annotation — Tim Hubbard / Serious Science

Bioinformatician Tim Hubbard on the process of identifying genes, protein genes and RNA genes, and how many genes are there in the human genome.

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'For a long time the view was that DNA makes RNA makes protein, that everything ends up with being a protein. When we annotated where these genes were, we always tend to look for the part of the gene that was going to make the protein. But as we’ve learned from looking at the RNAs that we could find, there’s many many cases where there’s no protein. In fact, there’s now a whole class of RNA genes which have been identified, many of which do have some functional importance. '

Tim Hubbard, Professor of Bioinformatics, King's College London

Genome Medicine: http://serious-science.org/genome-med...
Genetics of the Nature: http://serious-science.org/genetics-o...

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