Slow Metabolism, GLP-1s, and Peptides: What Actually Works (and What Doesn’t)

🎙️ Slow Metabolism, GLP-1s, and Peptides: What Actually Works and What Doesn’t
with Dr. Spencer Nadolsky, DO + Nataliia Sanzo, RDN, LDN || Episode 68

Is your metabolism really “broken”? Are GLP-1s like Ozempic or peptides like BPC-157 and NAD+ the missing piece in your Hashimoto’s healing journey?

In this can’t-miss episode of Hashimoto’s Nutrition Rx, Nataliia Sanzo sits down with Dr. Spencer Nadolsky, a board-certified obesity and lipid specialist (who also has Hashimoto’s!), to cut through the hype and get to the facts about weight loss resistance, thyroid health, metabolic adaptation, and the real role of medications like GLP-1s and peptides. From shocking myths to science-backed strategies, this episode will leave you better informed, more empowered, and ready to make confident choices for your health.

In this episode, you’ll learn:

✔️ Why Hashimoto’s does not automatically mean you can’t lose weight
✔️ The truth about “slow metabolism” and why most people misunderstand it
✔️ What GLP-1s really do and why food “noise” reduction is a game changer
✔️ Risks like thyroid cancer debunked with actual human data
✔️ Why peptides like BPC-157 and NAD+ might help (and what we don’t know yet)
✔️ How to avoid the most common GLP-1 mistakes like hair loss and muscle loss
✔️ The real deal on metabolic adaptation and “starvation mode” myths
✔️ How to safely microdose GLP-1s and why a personalized plan matters
✔️ What to do if you’re gaining weight while on GLP-1 meds
✔️ How resistance training and thyroid optimization protect your metabolism

Why you shouldn’t miss this episode:
This is one of the most informative and practical episodes we’ve done to date. If you’re curious about weight loss resistance, Hashimoto’s, peptides, or how to safely use modern therapies like GLP-1s, this is your roadmap.

Nataliia and Dr. Nadolsky blend clinical science, personal experience, and humor into a conversation that will shift how you think about your body, your metabolism, and your next steps.

Connect with Dr. Spencer Nadolsky on Instagram:
@drnadolsky
Link-   / drnadolsky  

Visit Dr. Spencer Nadolsky’s Website:
https://joinvineyard.com/join/

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00:00 Introduction
01:14 Meet Dr. Spencer Nadolsky
02:32 Understanding GLP-1 Medications and Thyroid Health
07:18 Can GLP-1s Support Metabolic Health Without Muscle Loss?
09:55 The Importance of Medical Guidance with GLP-1
11:17 Exploring Non-Weight Benefits of GLP-1
15:49 Future of GLP-1 and Microdosing
21:18 Peptides and Their Potential Benefits
24:12 Expert Opinion on NAD+ Injections
24:33 Personal Experience with BPC-157
25:02 The Importance of Placebo-Controlled Studies
27:47 Social Media and Weight Gain Myths
28:48 Understanding Metabolism and Weight Gain
31:57 High Cortisol and Weight Loss
34:28 Boosting Metabolism: Myths and Facts
42:40 Rapid Fire Questions with Dr. Spencer
44:16 Conclusion and Future Plans