The TRUTH About GLP-1s, Peptides & Muscle Loss (Doctors Explain)

GLP-1 medications are dominating the weight-loss and longevity conversation — but most people are missing the real science behind muscle loss, hormones, peptides, and mitochondrial health.

In this deep-dive panel discussion, leading longevity and hormone experts break down:
• Why GLP-1s can cause muscle loss if hormones aren’t optimised
• The role of testosterone, thyroid, growth hormone & circadian rhythm
• How peptides protect skeletal muscle during fat loss
• Why mitochondrial peptides are the future of anti-aging medicine
• The truth about bioregulator peptides and tissue-specific repair
• Why foundations like sleep, gut health, protein intake & resistance training matter more than any drug
• How split-dosing GLP-1s can reduce nausea, vomiting & hunger crashes
• Why peptides decline with age — just like hormones
• The next frontier in longevity, fat loss & metabolic health

This conversation separates real science from media fear-mongering and explains how GLP-1s, peptides, and hormones should be used together, not in isolation.

⚠️ This content is for educational purposes only and not medical advice.

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Chapters

00:00 – GLP-1s, Hormones & Why Muscle Loss Happens
01:18 – Fat Loss Without Damaging Metabolism
02:24 – Gut Health, Constipation & GLP-1 Side Effects
03:36 – Split Dosing GLP-1s (Why It Works Better)
04:44 – GLP-1s & Hormone Deficiency Explained
05:53 – Sleep, Training & Insulin Control Foundations
06:33 – Mitochondria: The Next Longevity Frontier
07:29 – Mitochondrial Peptides Explained (SS-31 & More)
08:22 – Replacing Peptides As We Age
09:25 – Bioregulator Peptides & Tissue Repair
10:39 – Prostate Health, PSA & Peptides
11:53 – Targeted Organ-Specific Peptides
13:08 – Oral vs Injectable Peptides (Do Orals Work?)
15:05 – Cycling Peptides & Avoiding Receptor Burnout
16:44 – Making Peptides Orally Bioavailable
18:47 – No More Injections? Future of Peptide Delivery
20:10 – Myostatin, Muscle Growth & Painful Peptides
22:00 – Where Beginners Should Start With Peptides
23:27 – The Future of Longevity Medicine


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