Position Effect | Silencing of a Gene | B.Sc Genetics

Position effect is the effect on the expression of a gene when its location in a chromosome is changed, often by translocation. Position effect is also used to describe the variation of expression exhibited by identical transgenes that insert into different regions of a genome.
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Picture credit:
1. A HUSH for transgene expression by Thijn R. Brummelkamp, Bas van Steensel. DOI: 10.1126/science.aac6529
2. Regulation of Gene Structure. https://www.coursehero.com/sg/cell-bi...
3. Histone acetylation and deacetylation: importance in inflammatory lung diseases by P.J. Barnes, I.M. Adcock and K. Ito. DOI : 10.1183/09031936.05.00117504
4. https://www.researchgate.net/figure/M...