hCG Explained: Effects on Testosterone, Fertility, and Testicular Function

hCG Explained: Effects on Testosterone, Fertility, and Testicular Function

What is hCG — and why is it often used alongside testosterone therapy?

In this video, Dr. Chancellor Harn breaks down the physiological role of human chorionic gonadotropin (hCG) in men’s health. You’ll learn how hCG mimics luteinizing hormone (LH) to stimulate the testes, helping to maintain intratesticular testosterone production, preserve testicular size, and support spermatogenesis — even in the presence of exogenous testosterone.

Dr. Harn also explains the broader implications of suppressing the hypothalamic-pituitary-gonadal (HPG) axis with TRT, and how hCG can be used strategically to preserve testicular function and fertility. If you're on testosterone therapy or exploring your options, this video offers a clear and clinically informed perspective on how hCG fits into the bigger hormonal picture.

▶️ For those considering TRT or seeking to maintain fertility and testicular health, this video provides valuable insight into how and why hCG may be clinically utilized.

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⏱ Video Chapters:
0:00 – Introduction
0:20 – What Is hCG? Its Native Role in Women
0:37 – How the HPG Axis Regulates Testosterone Production in Men
1:33 – hCG Structure and Its Similarity to Luteinizing Hormone (LH)
2:25 – How hCG Functions as an LH Mimetic to Stimulate Testosterone
2:35 – When to Consider hCG: Key Lab Markers (Total T, Free T, SHBG, LH, FSH)
2:45 – Primary vs. Secondary Hypogonadism: Why It Matters for hCG Use
3:53 – Common Causes of Secondary Hypogonadism and hCG’s Clinical Role
4:30 – Why hCG Is Sometimes Used Before Starting TRT
5:15 – Using hCG Concurrently with Testosterone Therapy: Clinical Rationale
7:40 – Should All Patients on TRT Use hCG?
8:23 – Can Fertility Be Maintained While on TRT?
10:20 – Summary and Final Thoughts (Including Extra-Gonadal LH Receptors)

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Medical Disclaimer:
This video is for general informational and educational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Viewing this content does not establish a doctor–patient relationship. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition, hormone therapy, supplements, or treatment plans. Do not disregard professional medical advice or delay seeking it because of something you have seen or heard in this video.

Compensation Disclosure:
Some of the links provided in this description may lead to third-party platforms where I receive a commission or other financial benefit. This disclosure is made in accordance with applicable regulations concerning transparency and material financial relationships.