Pharmaceutics CH-19.4| Stability, Methods Of Dispensing, Container Labelling & Storage Of Suspension

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Here, we have discussed about Pharmaceutics CH-19.4| Stability, Methods Of Dispensing, Container Labelling & Storage Of Suspension and prepared a best content for you so watch the complete video until the end and read the description below.

*Stability Of Suspension
The most stable pharmaceutical suspensions are flocculated i.e the suspended particles are bonded together physically to form a loose, semi rigid structure .
The non flocculated suspensions can be made stable by decreasing the particle size of the suspended material or by increasing the density and viscosity of the vehicle

*Methods Of Dispensing Suspension
1.Suspensions containing diffusible solids
2.Suspensions containing in diffusible solids
3.Suspensions containing precipitate forming liquids
4.Suspensions produced by chemical reactions

*1.Suspensions containing diffusible solids
Introduction :-
Suspensions containing diffusible solids Contains insoluble drug particles which are light in weight and readily mix with water and remain suspended throughout the liquid for sufficient period of time after shaking
Example: calcium carbonate, magnesium trisilicate, rhubarb powder ,light kaolin

General method of dispensing
Powder all the solid ingredients and add enough vehicle to form a smooth cream
Add more of vehicle to make it pourable
Remove if any foreign particle present by passing through muslin cloth
Rinse the mortar and pestle with successive volume of vehicle until they are quite clean
Add if any liquid ingredients
Add more of vehicle to adjust the final volume and mix thoroughly by shaking the bottle
Example: Kaolin mixture

*2.Suspensions containing
In diffusible solids
Introduction
Suspensions containing in diffusible solids Contain substances which do not dissolve in water and do not remain evenly distributed in the vehicle for sufficient period of time
Example: calamine, zinc oxide ,hydro cortisone, aspirin, phenobarbitone 

*3.Suspensions containing
Precipitate Forming Liquids
Introduction
Suspensions containing precipitate forming liquids Contains liquid substances that is precipitated on addition of water.
These liquid substances are insoluble and indiffusible and it is diificult to redisperse on shaking.
Example: compound benzoin tincture, myrrh tincture 

*4. Suspensions Produced By Chemical Reaction
Some of the suspensions are prepared by the chemical reactions between the ingredients used in the formulations.
In this reactants are highly diluted and mixed together to form very finely divided precipitates that can be easily distributed throughout the liquid by shaking.
The precipitate so formed are diffusible in nature.
Hence there is no need of adding any suspending agent
Example: sulphurated potash and zinc sulphate mixture





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