How the MTHFR Gene Affects Fertility: Folate Metabolism & IVF Success

In this episode, fertility dietitian Catherine Chong explains the MTHFR gene and its crucial role in folate metabolism, discussing why it matters for your fertility journey. Whether you're trying to conceive naturally or going through IVF, understanding the MTHFR gene's impact on both male and female fertility can be a game changer. Catherine explores current research and explains how MTHFR variants may affect your fertility health and outcomes.

Here’s what we’ll cover:
1. What is MTHFR?: Learn about this enzyme’s role in folate metabolism and DNA synthesis.
2. MTHFR Variants (C677T & A1298C): Discover how these genetic variations can impact your body’s ability to process folate and what this means for your fertility.
3. MTHFR and Female Fertility: Explore the link between MTHFR mutations and risks such as neural tube defects, elevated homocysteine levels, and poor oocyte prognosis in IVF.
4. MTHFR and Male Fertility: Learn how MTHFR polymorphisms can affect male fertility, with potential links to oligozoospermia and azoospermia.
5. Folate Supplementation (Folic Acid vs. 5-MTHF): Understand the importance of choosing the proper folate form and how working with a fertility dietitian can help you find the right approach tailored to your needs.

👉If you want to dive deeper into optimising your fertility, don’t forget to take our Egg Health Quiz and download our free starter guide: https://catherinechong.com.au/fertili...

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Disclaimer:
The information in this video is for educational purposes only and is not a substitute for professional medical advice. It is not intended to diagnose, treat or prevent any health condition. Always consult a qualified healthcare provider before changing your diet, medications, supplements, or treatment plan. Pristine Fertility is not liable for any actions taken based on this information.