Young Blood Can Rejuvenate Old Brains w/ Dr. Tony Wyss-Coray

In this episode, we are joined by Dr. Tony Wyss-Coray to discuss his groundbreaking research on brain resilience and aging.

He explains how systemic factors, particularly proteins in the blood, influence cognitive function and the aging process.

The discussion covers the role of proteomics, machine learning, and the potential of parabiosis and plasma infusions in developing therapies for age-related diseases like Alzheimer's.

Dr. Wyss-Coray emphasizes the importance of understanding the biological markers of aging and resilience to create targeted interventions for healthier aging.

Learn more about Dr. Wyss-Coray:
https://brainresilience.stanford.edu/
https://www.verobioscience.com/
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00:33 Introduction
03:40 Young Blood Experiments
06:51 Understanding Proteomics
08:36 Types of Proteins Identified
09:29 Machine Learning and Protein Fingerprints
11:03 Proteomics and Aging Pathways
13:21 Predicting Brain Disease
16:17 Correlation vs. Causation
18:45 Parabiosis and Plasma Exchange
21:50 Why Not Plasma Infusions?
25:25 Albumin-Only Approaches
26:30 New Therapeutic Approaches
28:00 Cognitive Resilience Patterns
32:41 Lifestyle Factors and Protein Signatures
34:20 Hormones and Aging
34:39 Stanford Brain Resilience Initiative