Health Effects of Sugar & Processed Foods || Dr. Robert Lustig || Andrew Huberman

In this episode, Dr. Robert Lustig neuroendocrinologist, UCSF professor, and bestselling author explains why the traditional “calories in, calories out” (CICO) model is incomplete. We discuss how macronutrients, fiber, and especially sugar particularly fructose alter metabolism, insulin, and organ health. The conversation covers how liquid sugars and highly refined foods impact the liver, brain, gut, and mental health, and how fructose can drive addictive eating behaviors similar to drugs of abuse. We also examine sugar’s role in obesity, disease, and how the food industry engineers ultra-processed foods to hijack appetite and cravings. This episode offers practical insights into how food choices affect metabolism, brain function, and long term health.In this episode, Dr. Robert Lustig neuroendocrinologist, UCSF professor, and bestselling author explains why the traditional “calories in, calories out” (CICO) model is incomplete. We discuss how macronutrients, fiber, and especially sugar particularly fructose alter metabolism, insulin, and organ health. The conversation covers how liquid sugars and highly refined foods impact the liver, brain, gut, and mental health, and how fructose can drive addictive eating behaviors similar to drugs of abuse. We also examine sugar’s role in obesity, disease, and how the food industry engineers ultra-processed foods to hijack appetite and cravings. This episode offers practical insights into how food choices affect metabolism, brain function, and long term health.